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avandia risks tagged articles (0-50 of 2601)

  • Avandia Drug Receives Requests for Label Change - A group of physicians recently petitioned the U.S. Food and Drug Administration (FDA) to change the labeling of a type 2 diabetes drug known as Avandia (rosiglitazone maleate). The request for the labeling change comes from the Physicians Committee for Responsible Medicine (PCRM) who would like to see a vegan diet recommendation on Avandia, which is marketed by GlaxoSmithKline. PCRM believes that a vegan diet is a safer alternative to consuming Avandia. According to the organization' s Web site, PCRM was established in 1985 to promote "compassionate and effective medical practice, research and health promotion" among laypersons, physicians and doctors.
  • Avandia Makers Receive Warning - GlaxoSmithKline, makers of the type 2 diabetes prescription drug known as Avandia, recently received warnings from the U.S. Food and Drug Administration (FDA) after the company withheld post-marketing research information on Avandia. Rosiglitazone maleate is the generic name of Avandia, which is taken orally to control insulin levels in the body. Avandia was once reportedly the best-selling diabetic drug around the world, however, a study published in the New England Journal of Medicine reported results from clinical trials of the drug, which found Avandia to have severe side effects on individuals both with a history of heart disease and without. According to the May 2007 report, Avandia patients had a severely increased risk of cardiovascular-related conditions and those risks increased the longer an individual was on the drug.
  • More Bad News for Avandia - Heading into 2007, Avandia was one of the best selling prescription medications in the United States. However, a string of negative studies may change that. Recent studies have linked the diabetes drug to heart attacks and bone fractures.
  • Diabetes Drug Avandia Linked to Possible Serious Side Effects - Diabetes is a serious ailment in modern America, with recent figures from the American Diabetes Association citing more than 20 million Americans afflicted with the disease, in addition to the roughly...
  • Depression Now Hand In Hand With Diabetes - Researchers at the University of Alberta (UA) recently discovered an increased risk of developing type 2 diabetes among individuals with depression. A study, published in Diabetes Research and Clinical Practice, found that patients who have been diagnosed with depression may have a 30 percent increased risk for developing diabetes. Lauren Brown, the lead author of the study, researched the history of 2,400 individuals who had been diagnosed with depression.
  • Scientists Link Avandia to Bone Fracture and Osteoporosis Risk - Millions of Americans suffer from a form of diabetes, and with increasing waistlines comes an increase of type 2 diabetes especially. However, there are many type 2 diabetes drugs available on the market including Avandia.
  • Improving Health Among Heart Failure Patients May Improve Outcome - Heart failure patients that exercised were more likely to have a positive outcome even while receiving excellent care than those receiving the same care who were not exercising, according to a recent study from the Duke University Medical Center.
  • Children With Weight Problems Showing Signs of Aged, Clogged Arteries - At the American Heart Association’s (AHA) annual scientific sessions held November 11 in New Orleans, scientists revealed that obese children and teenagers have carotid artery walls similar to those of an individual nearly three decades older.
  • Patient Safety - Instead of asking is a drug safe we should ask about patient safety. The reason being is the drugs that the FDA approved without long enough trial periods are on the market. So now the drugs are being sold as safe and the patients may not be.

  • Patients Studied in Aspirin Trial to Improve Heart Disease Among Type 2 Diabetes Patients - A study that was recently conducted and published in an issue of the American Medical Association discovered that type 2 diabetes and at-risk heart disease patients saw now decrease of antherosclerotic events, clotting of the arteries, while consuming a low-dose treatment of aspirin unless they were 65 years of age or older. The American Diabetes Association (ADA) reports that the development of diabetes means more than just managing insulin levels, but it also requires the management of potential risks such as heart disease, heart failure and stroke. According to the ADA, "people with diabetes must also manage blood pressure and cholesterol and talk to their health provider to learn about other ways to reduce their chance for heart attacks and strokes." What is Cardiovascular Disease?
  • Surgerical Procedures Including Knee and Hip at a High - General advancements in surgery and prostheses, combined with a lack of medicines for osteoarthritis, have caused doctors to perform more hip and knee replacements recently. Although the procedures are still mostly performed on people over 65, there is a growing population of individuals who range from 38 to 56 who are getting hip and knee implants or prostheses.
  • Developing Stevens-Johnson Syndrome and How to Deal - Each year, individuals seek medical attention for various illnesses and ailments, and they are directed to either prescription or over the counter drugs to help heal them. But when nearly 150,000 deaths can be attributed to adverse drug reactions within an individual, it makes a patient an unknowing victim. Two of the most common inflammatory skin diseases due to poor reactions to over the counter and prescription drugs are Stevens-Johnson Syndrome (SJS) and a form of SJS known as Toxic Epidural Necrolysis Syndrome (TEN). Many different drugs can trigger SJS, but anti-convulsants, antibiotics and anti-inflammatory drugs are most consistently responsible for causing SJS. While anyone can develop SJS, a Caucasian predominance has been reported. It is most commonly seen in children and in women (a 2:1 ratio compared to men), and can lead to death if left untreated.
  • Individuals Prone to Developing Diabetes May Reduce Risk With Exercise - The diabetic community in America continues to receive hardships among avoiding developing the disease as well as overcoming controversial diabetes treatments with severe side effects. However, researchers are continuing to work toward non-pharmaceutical alternatives to the condition. For example, a study from the Glasgow University in England found that individuals who are at an extremely high risk of developing the potentially fatal condition of type 2 diabetes can actually reduce their risk by nearly 22 percent with seven weeks of continued exercise. The study, led by Dr. Jason Gill on behalf of the British Heart Foundation (BHF), tested 70 women for seven weeks. The women were divided into two groups of those with type 2 diabetic parent(s) and those with no predisposition to type 2 diabetes.
  • Dangerous Side Effects of Everyday Benzene - Did you know that the toxic effects of benzene exposure can show up as late as 29 years after the first exposure? Clearly, the health risks of occupational or other benzene exposure are grave. Benzene, classified as a "Class A" carcinogen by the Environmental Protective Agency (EPA), is an extremely harmful chemical that is responsible for diseases such as Hodgkin's disease, various respiratory and skin disorders, and even leukemia. Though benzene has a strong odor, it is clear and colorless.
  • TNF Inhibitors as Treatments - The John Hopkins Medical Center reported that TNF blockers, also known as tumor necrosis factor (TNF) inhibitors, are a group of drugs that suppress continued inflammation found in certain conditions. The drugs are considered autoimmune disorder drugs and first became available to the market in 1998, ten years ago. What Are TNF Inhibitors? TNF-alphas are described as cytokines, also cell protein, according to the Mayo Clinic.
  • Gastric Acid Treatments Associated With Serious Risks - Individuals suffering from any of the several conditions associated with gastric acid and who are taking Proton Pump Inhibitors (PPIs) may find themselves at more of a risk for osteoporosis and bone fracture than gastric acid production. In August 2008, the Canadian Medical Association Journal found that PPIs may reduce calcium absorption, thus causing early onset osteoporosis and bone fracture among patients, especially those taking PPIs for five to seven years or longer.
  • Vitamin C Could Affect Mesothelioma Treatments - In a recent issue of Cancer Research, the study indicated that among mesothelioma cancer patients who are receiving chemotherapy treatments, those who have consumed vitamin C may see a decrease of effectiveness. According to the study, cancer victims should be very aware of the potential risk of consuming vitamin C during chemotherapy treatments because achieving a positive outcome during treatments is difficult enough without additional setback. Chemotherapy and Mesothelioma Cancer Chemotherapy is a form of treatment for cancer and can be administered in a number of ways, via a pill or through an needle injection.
  • Nicotine Addictions Stronger Today Than In Previous Decades - According to a study conducted by the Palo Alto Centre for Pulmonary Disease Prevention and the St. Helena Hospital in Napa, Calif., addictions to nicotine and smoking are actually stronger today than in previous generations. Researchers studied the "pre-treatment severity of nicotine dependence" of individuals in three studies that occurred from 1989 to 2006. Individuals who are extremely addicted to nicotine, smoking rose 17.5 percent during the years of the study. "Severe nicotine addiction had gone up between 1989 and 2006 and the percentage of smokers classified as highly nicotine dependent, as much as 32 percent," according to statistics obtained from the study.
  • Genes Linked to Leukemia Discovered - Researchers at the Washington University in St. Louis recently uncovered eight genes that may cause an individual to be predisposed to the development of leukemia. The researchers used "developed sequencing methods to look at the entire genome of cells from an acute myelogenous leukemia (AML) tumor and from the patient's skin, which helped narrow down and identify 10 varying genes between the tissues." The study was published in a recent issue of New Scientist magazine. 


  • Withdrawn from the Market: Redux and Fen-Phen - The diet drugs Fen-Phen (fenfluramine and phentermine), Pondimin (fenfluramine), and Redux (dexfenfluramine) aid in weight loss by altering the serotonin levels in the brain to suppress feelings of hunger. During the 1990s, doctors began to prescribe these drugs in combination to increase the weight loss effect. Studies have demonstrated serious potential health risks associated with the use of these drugs.
  • The Importance Of Credit Risk Management For Banking - The importance of credit risk management for banking is tremendous. Banks and other financial institutions are often faced with risks that are mostly of financial nature. These institutions must balance risks as well as returns. For a bank to have a large consumer base, it must offer loan products that are reasonable enough. However, if the interest rates in loan products are too low, the bank will suffer from losses.
  • Lead More Commonplace and More Dangerous Than Initially Thought - The dangers of lead paint and lead poisoning include a broad range of mental disorders and chronic disabilities. But lead paint and lead poisoning is especially dangerous for women, who run the risk of passing dangerous lead exposure on to developing fetuses while pregnant. Additionally, the following are tips that will help a pregant woman avoid lead exposure: Clean Up! Cleanliness is next to godliness...and can help pregnant women escape the dangers of toxic lead exposure. Pregnant women should clean the house when they see the presence of chipping paint or dust - both of which can contain lead particles. Cover chipping paint in your home with duct tape, plastic or contact paper, and vacuum dust whenever possible.
  • Asbestos Lawyers and Litigation - Developing an asbestos lawsuit can be a challenging and scary process, which is why finding an asbestos attorney who can breakdown the legalities of a case is important. For example, understanding that defendants in an asbestos lawsuit are those allegedly responsible for the asbestos exposure is important to know.
  • Dry Eye After Lasik - You've heard there are risks. This is, after all, a surgery. One shouldn't expect it to be risk free. With lasik eye surgery, one of those risks is dry eye. What's the big deal? So what if the eyes are a little dry? Before you pay your hard earned money... before you place your eyes under a super powerful laser... ...just know that one potential side effect is discomfort from dry eye. Sometimes, it's not just temporary.
  • Cancer Patients May Not Be Receiving On-Time Treatment Care - Several inconsistencies among primary care trusts (PCTs) may be delaying the approval of treatments for cancer patients and mesothelioma cancer patients, according to a study from the United Kingdom's Macmillan Cancer Support organization. The inconsistent patterns, according to the survey, may result in cancer patients, such as mesothelioma patients, suffering from delays in receiving treatments. Because mesothelioma cancer is a condition in which the life expectancy can be approximately 12 months from diagnosis, it is imperative that any treatments or clinical trials that a patient can participate in become available to them immediately as time is of the essence. Seventy-six percent of the time, treatment costs were taken into account prior to a patient being approved or declined for medical treatments, according to the survey.
  • Living With Nephrogenic Systemic Fibrosis - Nephrogenic Systemic Fibrosis (NSF) was first discovered in 2000 and the cause of this disease is still unknown to medical professionals and scientists.
  • What is Vinyl Chloride? - Vinyl Chloride is a chemical compound that can be quite serious for individuals who are affected by it; and while it's use is not as wide-spread or apparent as many other contaminants it can be just as dangerous. In fact the American Chemical Society (ACS) has assigned a Chemical Abstracts Service (CAS) registry number to it for identity reasons and Vinyl Chloride is known as 75-01-4. To learn more about research and effects surrounding Vinyl Chloride, it is advisable to contact the ACS, which keeps documentation on the chemical. The Environmental Protection Agency (EPA) is another body regulating vinyl chloride. The EPA has calculated an inhalation unit risk estimate of 8.8 10-6 (g/m3)-1 for vinyl chloride lifetime exposure.
  • What is Premises Liability? - When an individual is on another's property, whether trespassing or invited, and the individual is harmed, there are many premises liability details that must be investigated. Was the Plaintiff an Invitee, Licensee or Trespasser? Premises law is predicated on the litigant's presence on the premises in question. Under legal terms the litigant is known as the plaintiff of a case. The property or premises owner is called the defendant for purposes of the premises liability lawsuit.
  • Better Understanding Osteoporosis - The National Osteoporosis Foundation (NOF) reports that osteoporosis is a condition in which bones in the body become very fragile and extremely prone to breaking or fracturing. The NOF also reports that if left untreated, "osteoporosis can progress painlessly until a bone breaks." The most common bones that break within an osteoporosis victim include the wrists, hips or spine. How Common is Osteoporosis? Currently, approximately 10 million Americans suffer from osteoporosis, which is more common among women, affecting nearly 8 million women and only two million men.
  • The Risks Of Home Mortgage Refinancing - Are there risks involved in home mortgage refinancing? Yes, there are. Know a few risks to watch out for through this article. Home mortgage refinancing may be the wisest decision you make to improve your current financial situation. It can give you a new hope and a new start. With lower interest rates and monthly payments, it sounds like a big relief from the financial burden you may be carrying now. However, although home loan refinancing proves to be effective in helping you with your finances, there are a few risks involved. You probably know how there are risks involved in almost every major decision you need to make.
  • Alli Weight Loss Pills Are a Big, Fat Lie - Every year more than 70 million people resolve to lose weight by going on a diet, which feeds the big, fat $58 billion diet and weight-loss industry. After all the money is wasted, the cold, harsh reality is that fewer than 5 percent of dieters will realize long-term results. The other 95 percent will regain all the weight they lost, and then some. How can an industry survive with such a low success rate? How can it be legal to market and sell something that has a proven track record for failure? Now consumers have a brand new diet deception being marketed to them backed with over $150 million in marketing to spin the weight-loss lie. Buyers searching for the right solution to their struggles with weight loss now have access to the new FDA-approved over-the-counter weight-loss drug Orlistat, also known as Alli.
  • Medical Journal Finds Jaundice Treatment Decreases TBI Among Infants - The New England Journal of Medicine recently reported in its October issue that if an infant is given an aggressive jaundice treatment early on, that infant will be less likely to suffer from a brain injury or neuro-developmental issues in the future, according to a study conducted by the University of Texas Medical School.
  • Understanding Credit Risk Management - Companies and other institutions, such as banks, are often faced with certain risks. Risk is always a part in every business. But if the risk involved is financial in nature, companies must come up with a system that can help manage risk. In the financial world, credit risk management plays an important role in managing the risks that come with credit and investment.
  • The Uncertainties Of Online Marketing And Buying - Business always comes with risks. These risks are for both consumer and marketer. However, some people still conduct business despite these risks because there are ways to mitigate them. It just depends on the person wishing to do business. The presence of the Internet has afforded businessmen an avenue to easily market products to a wider audience than before. Even small businesses have jumped at the newfound opportunity of having to do business with people around the world. However, marketing through the Internet still has its risks which both the seller and the buyer must be aware of. So what are the risks that one can expect from the act of doing commerce using the Internet? One of the most significant risks associated with e-commerce that most buyers are apprehensive of is the fact that they are exposed to threats to their privacy.
  • Operating an Automobile and Talking on a Cell Phone Can be Risky - As cell phones and other gadgets accompanying wireless communication has increased tenfold over the last decade, providing more convenience for individuals on the go it has also increased the risks of deadly automobile accidents on the road as well.
  • Legalities of a Trainer and Trainee - There have been relatively few legal opinions about litigation between athletic trainers, competitive athletes and sports accidents or injuries. However the courts have recognized that a duty does exist between the parties.
  • Dangers of Medtronic Defibrillators - An implantable cardioverter defibrillator (ICD) is a device that is implanted in the chest to monitor for and, if necessary, correct episodes of abnormal heart rhythm (arrhythmia). ICDs can generate (1) a series of precisely timed low-intensity electrical pulses to reset the heart to normal rhythm when the heartbeat becomes faster than normal (ventricular tachycardia), and (2) electric shocks that may feel like a sudden kick in the chest to stop potentially fatal quivering of the heart (ventricular fibrillation). In addition, the ICD may be programmed to work as a pacemaker and send small electrical signals to pace the heart whenever it detects an abnormally low heartbeat (bradycardia). These electronic medical devices are placed in the body to prevent cardiac arrest from severe ventricular tachycardia.
  • Is too much caution holding you back from business success? - Are you being held back from business success because you're avoiding things you need to do? Of course, when you're running a business it's important to be prudent. Prudence is defined as "caution in managing your activity." But alongside sensible caution, it's sometimes necessary to take a little risk. If it was easy, everybody would do it. That's why successful businesses are the ones that actually take a little bit of risk in order to move themselves forward. Some people are put off because of fear of mistakes. William Shakespeare said: "Our doubts are traitors, and make us lose the good we oft might win by fearing to attempt." In other words if we allow ourselves to be victims of self-doubt, we deny ourselves the potential rewards of success.
  • Can The Risks Of Lap Band Surgery Be Life Threatening? - You’ve tried all the diets out there, feel like you’ve worked yourself to the bone exercising, but nothing seems to work. Obesity makes you feel lousy, and you just want to get your life back. You may be thinking of getting weight loss lap band surgery, and wondering about the risks. Is it all easy street after the surgery, or will you be at risk for further health problems-- or even death? The answer, unfortunately, is that you will. Lap band surgery is major surgery… and like any major surgery, it comes with a whole host of risks. And yes, one of those risks is death. Sounds pretty scary, doesn’t it? While lap band surgery isn’t a decision to be entered into lightly, if you’re considering the surgery, you shouldn’t let the risk of death scare you too much.
  • Asbestos Legislation Aims to Increase Mesothelioma Funding - In May 2008, a six-year long battle for many asbestosis mesothelioma victims ended, as a legislative bill was finally introduced to Congress. The legislation, known as H.R.
  • Limiting Business Risks And Reaching For The Stars - Entrepreneurialism in business is the driving force behind success. While everyone may naturally associate entrepreneurialism with business, they are not necessarily linked concepts - a business person may not be an entrepreneur, while an entrepreneur might not be the finest example of entrepreneurialism in practice. Nevertheless it is critical to encourage this behaviour, for the health and well-being of the global economy.
  • The Risks Of Liposuction - Before you get too involved with planning the date of your liposuction, make sure you have done your homework. Many people do not realize some of the greater risks of liposuction. Despite the fact that the industry has become better developed and most of the risks have been reduced, they have not been eliminated, and being aware of them ahead of time is a good way to educate yourself before you sign the papers. If you are not good at dealing with pain there are a few things you need to consider. First of all, while the operation itself should not be excruciatingly painful, you will still experience discomfort and pain for days or weeks after the operation.
  • Self-Confidence - 3 Things You Can Do When You Have None - Self-confidence is one of the keys to achieving success – you hear that everywhere. Most people think self-confidence is a result of success, but it’s actually an ingredient of success.
  • A Gastric Band Can Sometimes Be A Life Band - For many people who have battled against their weight for years and tried just about every diet and exercise program available, gastric bypass surgery, such as adjustable gastric banding, can offer a tempting alternative and is certainly an option to be considered and discussed with their doctor. For some people however the gastric band is much more than simply a solution to their weight problem and can literally save their lives. Severe or morbid obesity is not simply a weight problem and can bring with it a host of very serious and, in some cases, life-threatening conditions such as sleep apnea, high blood pressure, heart disease, diabetes and others.
  • Traumatic Brain Injuries Resulting from Sports Participation: A Resource Guide - Traumatic brain injury (TBI) occurs when the head strikes or is stuck by an object. The head does not have to experience an external blow for the brain to be injured. Brain damage can occur when the head is pushed strongly against the skull, such as with whiplash. A concussion is a milder form of traumatic brain injury, where full recovery usually occurs without major long term effects, unless an individual suffers more than one concussion in succession. Repeated brain injuries have a cumulative effect resulting in more severe and more prolonged post-concussion symptoms. If an individual incurs a second concussion while the symptoms from a previous concussion still persist, serious and dangerous conditions or even death can occur. This condition is called second-impact syndrome (SIS).
  • Hurricanes Increase Risk of Asbestos Exposure - Individuals who have been affected by Hurricane Ike are still dealing with the after affects including exposure to asbestos fibers from destruction of homes caused by flooding. According to the International Herald Tribune, following the hurricane, homes and roads were left with debris as well as a toxic sludge made of mud, human waste, lead, gasoline and asbestos in the wake of floodwaters, which have since receded. The potential for these fibers to dry and become airborne may be serious and could cause an increased risk of mesothelioma cancer among hurricane victims as well as nearby residents because of asbestos exposure. What is Asbestos Exposure? Asbestos fibers become airborne and cause the development of cancerous cells among victims.
  • The Possible Risks You Face When Selling Your Own Home - Recently you’ve may have taken notice to the huge change in how real estate is sold, instead of the traditional method of hiring a real estate agent to sell your home more people are now selling their homes by themselves. Although the benefits are clear when choosing to sell your own home often time’s homeowners will neglect to realize and analyze the risks involved with selling your home and believe me there are some definite risks when choosing this route.
  • Is Fractional Ownership High Risk? - When we do anything in life we expose ourselves to risks. Walking down the street, driving your car, even staying in bed for the day all have associated risks. Understanding the risks associated with any decision is important because it enables you to make informed choices.
  • Emotional Risks From Being Overweight - There's a physical emphasis on the problems being overweight can cause. In other words, the warnings about excess body weight are usually warnings about physical risks. It's a sensible approach: there are numerous physical risks to being overweight, including risks to the heart, the entire circulatory system, the digestive system, and other regions of the body as well.
  • The Risks of Banking Offshore - If you are looking for a way to keep your money safe, keep your transactions private and lower your tax burden, you may be considering opening an offshore bank account. An offshore bank account can be a good idea for some people, but there are some things you should know before you set up your account. Unlike what you see in the movie's, offshore bank accounts are not illegal on their own.

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